THAT is HPTA Supraphysiological Overcompensation. Hmmm, look bad, feel bad and not care. During the pre-administration period we tested for Total Testosterone, Free Testosterone and Estradiol, then tested again at 14 and 42 days. There's a video showing a study where they give different amount of testosterone to each group. Just wondering if HCG therapy will suppress what little LH and FSH levels a TRT patient may have. HCGs effect on HPTA; Scroll down Bro - forums are below . Every single hormone in the body has a negative feedback loop. CONCLUSIONS I have a friend on deca, and i am going to be using fina in mine, so we are in a similar situation. When discontinuing a long-acting injectable ester, such as cypionate or enanthate, therapy to stop TRT is usually initiated roughly five days after the last injection, as the hormone levels start to fall. Seemed to be fine. Take precaution, research thoroughly and never take a shortcut and you will keep yourself in good health and be able to make the most out of every cycle you run, promote longevity and continue to lead a long and healthy life. Clomiphen, Anastrazole and HCGOh My (The Most Common PCT). Hmmm, still nothing to "positively" affect the Androgen Negative Feed-Back Loop. An HPTA restart will comprise of two phases, HCG and AI use to activate the testicles to be receptive to the LH/FSH pulse when the medications are discontinued. (No joke!) An integral part of the limbic system, the hypothalamus is involved in regulation of the internal milieu of the body or, said another way, for homeostatic control. Mechanism of Suppression. It sounds like you have more than one reason why FT is low, LH on the lower end and the only way someone could have FT at the bottom of the ranges is SHBG on the higher end. 05-21-2003, 08:20 PM #8. bigdelt69. HCG sees use in some PCT but that is a misconception because HCG works quickly and restores testicular volume giving the appearance of treatment however in the long run does not properly restart your HPTA. He is also advanced with testosterone replacement therapy TRT and HRT. Very long term TRT (20+ years) - risk of liver cancer? Testosterone Replacement, Low T, HCG, & Beyond. My HPTA has been screwed up for a few months now and I tried Sustain Alpha which doesn't seem to be working. You are using an out of date browser. Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. There are currently 1 users browsing this thread. This is simply not true for the majority of the cases. (Xeno comes from the Greek, meaning strange or foreign.). In regards to your second post, it sounds like you're talking about cellular hyperplasia vs. proliferation. Blood test results after 6 week clomid therapy from HPTA restart. JIMO you are 100% correct in this statement: "I was hoping that HCG would help convert cholesterol to pregnenolone to support adrenal productions to ensure proper cortisol reaction to the stimulus". Injecting 250 mg every two weeks exposes the body to higher peaks that injecting 125 per week. Blood test results after 6 week clomid therapy from HPTA restart. Have tried before and didn't feel any subject benefits but was doing a small dose of 125iu per day. The cycle was 3 months long. After phase 1 of the protocol has been completed successfully as determined by labs; we can initiate phase 2. It works by blocking more powerful and active estrogens from merging with the hypothalamic estrogen receptors. HPTA is a reference we give the combined function of the hypothalamus, pitultary gland, and testes so we can speak of them as a single system. DHEA and Pregnenolone are converted via enzymes to testosterone and estrogen, as well as host of other metabolites which are required for other hormones of the nuclear receptor family. In this podcast for iTunes our hosts Stevesmi and Da Mobster discuss - The science of what happens on cycle to your HPTA and when you come off. All these hormones have multiple functions which most dont understand, leading to many negative side effects. From my research clomid will get my hpta going again but it will also cause some intertesticlar e2 just like the hcg did. You're still shutting your system down. There may be cases where a patient cannot maintain adequate testosterone production on their own after discontinuing hormone supplementation. If this is the case then recovery to baseline should be relatively rapid, a few weeks at most. Performance & security by Cloudflare. This includes the stimulation of LH production in the pituitary or stimulation of the testicular cells to produce testosterone. This program has been tried and tested hundreds of times. Once testosterone has stopped being produced, it no longer sends this negative signal, and GnRH eventually begins to do its job again. And with the suppressed LH levels eventually you will get testicular atrophy (shrunken testicles) that produce very little testosterone and in some cases bodybuilders have been so severely shut down after years of steroid abuse that when they eventually do come off even a 300lb male may have less testosterone than a 50lb 6 year old girl, which . Can that be done? The first and most important How-to answer in the optimization of human performance begins with HPTA Supraphysiological Overcompensation: The Holy Grail of optimized natural human performance enhancement. Definitely appreciate the response. So ending HCG administration sometimes only brought on another crash. Many attempt recovery of their natural testosterone levels and fail because they have the wrong dosing structure, not one backed by hundreds of clients successfully restarting for 5+ years going strong. About Business Point; Blog; Contact; Home; Home; Home; Our Services. Pregnenolone being a very important neurosteroid and supports healthy brain function, modulates NMDA receptors and has been proven to reduce negative effects induced by schizophrenia (this example to show how powerful it is, not that you have schizophrenia). True TRT should shut down someones HPTA and create a negative feedback environment permanently, correct? As a result of all of this excess testosterone floating aroundthe body, there is a lot of aromatization to estrogens and an overabundance of androgen receptors of the hypothalamus being over-stimulated. Why do you need to shut down your hpta to jump start it? Coming into this cycle and having no experience with AAS aside from observations of a few good friends cycles, heavy and mild, long and short length, and a few message boards I followed for a few years back in my early and mid 20s I was quite hardline with the thought of 1 cycle, standard or close to it length, standard PCT - punch in punch out. Dan was sharp (he kept us all thinking), but he missed on this one. If youre thinking about starting a TRT protocol, the first step is getting an estimate on cost. Clinical research was done sampling intra-testicular testosterone [ITT] inside the tests with find needle extraction [ouch!] . HPTA stands for hypothalamic-pituitary-testicular (or sometimes gonadal) axis. Powered by Discourse, best viewed with JavaScript enabled. Jun 28, 2014. Hard to fathom. . Say one was to use a blast and cruze method for a year or more and run HCG the entire time, wouldn't your boys be G2G once you dropped the hormones? This list is not all-inclusive, since there are similar medications sometimes used by specialists depending on their experience with the drug and their goals for the patient. Subjects were HPTA shutdown with T cyp injections, LH/FSH were close to zero in a couple of days. So ending HCG administration sometimes only brought on another crash. Question about HPTA shutdown. When attempting to restart the HPTA you need to take all 3 into account and make sure the conditions are right for the Axis to get rolling again. Most guys use hcg during a cycle to keep the testicles their normal size, other guys use it right after a cycle to get their testicle size back and to stimulate them into producing testosterone. Did you ever go down to a very clinical dose of testosterone (< 200 mg/week) for an extended time, say over 6 months, and have you kept any gains (if you were at genetic limit prior to starting)? do all ysl bags come with authenticity cards, south alabama track and field scholarship standards, parexel clinical research associate salary near berlin, World Record For Most Spacebar Clicks In 1 Minute. Heres what you need to know about the cost of TRT at Defy Medical. This hormone is sent out by the hypothalamus and signals the pituitary to release LH and FSH. (9), AI: Low dose aromatase inhibitor will keep estrogen low to make sure that it is not suppressing the HPTA and keep mood swings to a minimal. In women, hCG affects ovulation and fertility. Endogenous (made inside the body) testosterone production is predominantly a result of, and governed by, the HPTA (Hypothalamus-Pituitary-Testes-Axis). Using HCG during hormone supplementation can help the HPTA recover faster after hormones are discontinued. Researchers have also noted that total cholesterol levels decrease from between 4 weeks to 3 months. Testosterone Replacement, Low T, HCG, & Beyond. All information contained within this site is for informational purposes only. Don't fuck your system up. .with all that, Rick is a supplement designer and holds amazing knowledge of herbal products. This is how homeostasis is maintained in the human body. It's completely normal to have testicular atrophy during a cycle, you're shutting your system down. Depression, anxiety, and other mood changes, Loss of strength, muscle mass, and energy, PDE5 inhibitor like tadalafil or sildenafil to treat erectile dysfunction. It is commonly touted that once you start testosterone replacement (TRT) you are stuck with it for the rest of your life. In today's media-hysteria-managed environment, athletes, supplement companies and drug dealers alike are seen in the same shady light. Thanks guys, I will properly reincorporate HCG soon. Re: Suppression from hCG monotherapy. have there been any studies, or even anyone got any opinions, on the levels of hpta shut down with regards to dosage of trt. This is due significantly to un-natural (exogenous) exposure to the overabundance of plant-derived phytoestrogens (such as those found in soy products) and xenoestrogens in plastics and herbicides today. But this combination only helps clean up the effects of the Estrogen Negative Feed-Back Loop leaving the Androgen Negative Feed-Back Loop unaffected. Awards 0. Again, My cousin while he was natty was 174-176lbs at 12% bodyfat sitting at 5'6-5'7; pretty sure he would of able to get to 180-190lbs if he kept working out and eating the same. This is referred to as the negative feedback loop. I personally do not believe anything I cannot prove myself in the lab. Wasn't really sure how to title this but I have some questions and some assumptions Im wondering if are valid or not. I also agree that shutting it on and off is more damaging in the long run than longer runs with one PCT a year. Most negative side effects come from the use of AAS, not from the excess of natural endogenous testosterone itself. The Question You Really Want To Ask Why Don't "My Boy's" Do That Naturally? This is vital to minimise post cycle muscle losses. The mean receptor level reached a nadir which was 5--10% of that in the control testes, 3 days after the injection, after which it gradually . Steroids that can increase prolactin, mainly 19-nors, such as nandrolone and trenbolone, need to be taken with extra precaution. Your IP: In regard to everyone's favorite naturally occurring man-making androgen, testosterone is king of the muscle building anabolicsand your body can make WAY more than you need through HPTA Supraphysiological Overcompensation. I am not a doctor, but this is just what I have read. J Steroid Biochem Mol Biol. Kaplan ME, McGinnis MY. Any suggestions on a regimen to get back on track would be greatly appreciated. Department of Anatomy, Mount Sinai School of Medicine, CUNY, New York 10029. Just another site does hcg shut down hpta . It may not display this or other websites correctly. Great question asked and some very plausible explanations. 2003 Feb;68(2):370-4. Home; Products; About Us. Get on it if you aren't. Garden Grove, CA 92844, Contact Us! I am working with an endocrinologist who i am pretty sure has little experience with someone who is shutdown from steroid usage. "Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men" "J Clin Endocrinol Metab. New Bloodwork - Crashed Estrogen = What now ??? This hormone is an important contributor in the modulation of the somatotropic axis and can impair our testosterone production if not optimized alongside the other hormones. In order for your body to produce testosterone naturally again these three signals need to be functioning properly. By most accounts, nandrolone is an extremely mild steroid. Does it harm your hpta? Well, unless you are naturally gifted with 800 total t and free t at top of range Typically, if your HPTA is shutdown, that means your body's natural production of testosterone is no longer operating. Their may be little you can do about the SHBG, so any testosterone gains you make will quickly be bound up to SHBG and deactivated not allowing your FT to increase enough. . Exogenous testosterone will stop the signaling, but there are other hormones which will contribute to shut-down as well such as prolactin and estrogen. Certain hormones should be responding to treatment, and if they are not responding, adjustments can be made to the protocol. The increase in these hormones causes the testes to stimulate the Leydig cells to produce testosterone (by conversion of cholesterol). It does that by means of its neuroendocrine role in conjunction with the pituitary gland as well as by its influence on the the autonomic nervous system, which helps regulate body temperature, the cardiovascular system, and food and water intake. Of course the results are obvious: Increased muscle mass, decreased fat mass, a marked increase in metabolic rate, better focus, and improved performance in every manly area. 2 weeks in , will probably do 2 more weeks if not more. When the body recognizes elevated hormones in the blood, it prevents the pituitary from releasing LH, and without stimulation from LH, the testicles are unable to produce testosterone. Anabolic steroid users and those looking to increase endogenous androgen production alike, have used this so-called stack almost like a religious rite not realizing there was an error in its structure. 1993 Dec;77(6):1529-34. Put it this way, I was at my genetic limit before starting my cycle and then going into TRT. The action you just performed triggered the security solution. Live. It works, and we have the lab work to back it up along with testimonials. While on TRT therapy, you are shutting down your natural testosterone production. I did the trt treatment for one month and I am currently . Many doctors now refer to tongkat ali as being "herbal HCG" or herbal clomid but its perhaps better more like clomid this HCG because it forever stimulates your HTPA and never shuts it down like tribulus or HCG can.
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